Topogyne is the only registered misoprostol in Bulgaria having two indications – termination of pregnancy up to 49 day of amenorrhea, in consecutive application with mifepristone and preparation of cervix uteri for surgical abortion.
Off-label Topogyne is widely used in obstetric practice for birth induction, postpartum bleeding and others, but in different doses.
As part of the approved Risk management plan of Topogyne, Educational materials for medical specialists and patients including a safety card are distributed, so all doctors and women using the medicine are supposed to become acquainted with them.